Which of the following drug classes is associated with significant differences in metabolism based on gender?

Question

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Serotonin reuptake inhibitors (SSRIs) have been shown to have significant differences in metabolism based on gender. Women generally have slower metabolism for SSRIs compared to men, leading to higher plasma concentrations and potentially increased risk for adverse effects. This has been attributed to differences in the activity of certain enzymes involved in drug metabolism, particularly CYP2D6. The other drug classes listed do not have significant gender differences in metabolism.

Which of the Following Drug Classes Is Associated with Significant