Sulfonylureas May Be Added to a Treatment Regimen for Type

Sulfonylureas may be added to a treatment regimen for type 2 diabetics when lifestyle modifications and metformin are insufficient to achieve target glucose levels. Sulfonylureas have been moved to Step 2 therapy because they:

A) Increase endogenous insulin secretion
B) Have a significant risk for hypoglycemia
C) Address the insulin resistance found in type 2 diabetics
D) Improve insulin binding to receptors