A 66-year-old male was prescribed phenelzine (Nardil) while in an acute psychiatric unit for recalcitrant depression. The NP managing his primary health care needs to understand the following regarding phenelzine and other monoamine oxidase inhibitors (MAOIs):

Question

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A) MAOIs can interact with serotonergic drugs, leading to serotonin syndrome. Sumatriptan (Imitrex) is a serotonergic drug used for migraine headaches and should not be prescribed with MAOIs. 
B) MAOIs interact with tyramine-containing foods such as aged cheese, fermented meats, and soy sauce, which can lead to hypertensive crisis. The patient should be advised to avoid these foods while taking the medication.
C) Hypertensive crisis is a potential complication of MAOI use and can present with symptoms such as headache, tachycardia, sweating, and increased blood pressure. Immediate treatment with intravenous phentolamine or other antihypertensive medications is necessary to prevent cardiovascular complications.

A 66-Year-Old Male Was Prescribed Phenelzine (Nardil) While in an Acute