In muscular dystrophy, the protein dystrophin, which strengthens the sarcolemma by connecting the cytoskeleton with the extracellular matrix, is missing. What would be a consequence of these fibers lacking this important sarcolemma strengthening protein?
A) The sarcolemma would be weak and tear, allowing extracellular substances, including calcium ions, into the cell and disrupting muscle function.
B) The sarcolemma would become thick and fibrous, impeding ion exchange across it.
C) The sarcolemma would function normally, as this protein isn't important to muscle function.
D) The sarcolemma would shrink, compressing the contents of the muscle fiber and disrupting muscle function.
Correct Answer:
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