Leukocyte surface markers identify cell lineage and are helpful in differentiating neoplastic hematologic disorders. What is one method used to identify these surface markers?
A) Chamber counts
B) Leukocyte differential
C) Cytogenetic methods
D) Immunophenotyping by flow cytometry

Question

Quizplus · Accepted Answer

Immunophenotyping by flow cytometry is the best method to identify leukocyte surface markers, as it allows for the analysis of multiple markers on individual cells at a high throughput. Chamber counts and leukocyte differentials are basic methods for counting and classifying white blood cells, but do not provide detailed information on surface markers. Cytogenetic methods can provide information on chromosomal abnormalities, but are not specific to surface markers.

Leukocyte Surface Markers Identify Cell Lineage and Are Helpful in Differentiating