Antibodies to which component(s) are thought to complex with the phospholipids resulting in antiphospholipid antibody syndrome are:

Question

Quizplus · Accepted Answer

Antiphospholipid syndrome is characterized by the presence of autoantibodies against phospholipids and/or phospholipid-binding proteins. β₂-glycoprotein-1, prothrombin, protein C, protein S, and factor VII are among the phospholipid-binding proteins that are targeted by these antibodies. Complex formation between these antibodies and phospholipids can lead to thrombotic events and adverse pregnancy outcomes. Homocysteine, fibrinogen and fibrin, plasminogen, and plasmin are not directly involved in the pathogenesis of antiphospholipid syndrome.

Antibodies to Which Component(s) Are Thought to Complex with the Phospholipids