Which plasminogen activator (PA) is distinctive among the serine proteases because it does not circulate as a zymogen but is fully active toward its substrate plasminogen in a single-chain form?

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Quizplus · Accepted Answer

Tissue plasminogen activator (tPA) is unique among serine proteases as it is active in its single-chain form and does not require conversion from a zymogen to be active towards plasminogen.

Which Plasminogen Activator (PA) Is Distinctive Among the Serine Proteases