A lymph node biopsy from a patient with lymphadenopathy is performed. Which of the following findings would support the diagnosis of a reactive proliferation rather than a malignant lymphoma?

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Quizplus · Accepted Answer

A mixed population of cells varying in size, shape, and color is indicative of a reactive proliferation as opposed to a malignant lymphoma which generally shows a more uniform population of cells. Clonality, presence of large, bizarre cells, and mitotic activity are all features more commonly associated with malignant lymphomas.

A Lymph Node Biopsy from a Patient with Lymphadenopathy Is