A bone marrow sample is sent to the lab for cytochemical staining. MPO, SBB, and nonspecific esterase (NSE) have been ordered. Staining results come back as follows: MPO: positive SBB: positive NSE: positive
Based on these findings, what lineage(s) is(are) most likely affected?

Question

Quizplus · Accepted Answer

MPO and SBB are markers of myeloid lineage, while NSE is a marker of monocytic lineage. Therefore, both myeloid and monocytic lineages are likely affected.

A Bone Marrow Sample Is Sent to the Lab for Cytochemical