A patient blood smear shows oval macrocytes, a dimorphic population, and basophilic stippling. The peripheral blood also has 6% blasts. What is the presumptive classification based on these findings?

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Quizplus · Accepted Answer

The combination of oval macrocytes, dimorphic population, and basophilic stippling suggests a diagnosis of myelodysplastic syndrome (MDS). The presence of blasts in the peripheral blood indicates a possible progression to MDS with excess blasts, and a blast count of 6% indicates MDS-EB-1. It is important to note that a bone marrow biopsy and cytogenetic analysis would be necessary for confirmation and further classification.

A Patient Blood Smear Shows Oval Macrocytes, a Dimorphic Population