A bone marrow specimen is received in the cytogenetics lab. FISH analysis has been ordered. The laboratician performs the assay and notices that 96% of the patient's cells contain both 5q- and 12q- deletions. These cytogenetic findings are characteristic of:

Question

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The presence of both 5q- and 12q- deletions is a characteristic cytogenetic abnormality seen in myelodysplastic syndromes (MDS). This finding is not typically seen in chronic myeloid leukemia (CML), acute myeloid leukemia (AML), or acute lymphoblastic leukemia (ALL).

A Bone Marrow Specimen Is Received in the Cytogenetics Lab