Cell lineage of leukemic blasts can be determined by:
A) Morphology, cytochemical stains, cell concentration
B) Cytochemical stains, immunophenotyping
C) Presence of Auer rods and Pappenheimer bodies
D) Immaturity of cytoplasm and presence of nuclear phi bodies

Question

Quizplus · Accepted Answer

Leukemic blasts can be classified into various lineages based on immunophenotyping, which involves labeling the cells with fluorescent antibodies specific to certain cell surface markers. This allows the determination of the cell lineage based on the presence or absence of these markers. Morphology and cytochemical stains can provide some information but are not specific enough to differentiate between different types of leukemic blasts. The presence of Auer rods and Pappenheimer bodies are characteristic features of certain types of leukemias but are not sufficient to determine the cell lineage. Phi bodies are rare nuclear inclusions found in some leukemic blasts, but their presence alone is not specific enough to identify the cell lineage.

Cell Lineage of Leukemic Blasts Can Be Determined By