An adult patient's blood sample was collected in an EDTA blood collection tube for a CBC. The automated WBC count was 2.1 × 10⁹/L. Upon microscopic examination of the cells, the laboratory professional noted that the neutrophils adhered to the erythrocytes. What corrective action should be taken in this situation?

Question

Quizplus · Accepted Answer

The presence of neutrophils adhered to erythrocytes can cause inaccurate reading in the automated cell counter resulting in a falsely low WBC count. Recollecting the blood from a finger stick and making manual dilutions will eliminate the interference and provide an accurate WBC count. Using heparin, citrate or plain red top tube will not address the issue of neutrophil adherence to erythrocytes.

An Adult Patient's Blood Sample Was Collected in an EDTA