Predict the effect of p16 on the cell cycle of dividing cells.
A) Increases cell cycle progression
B) Decreases cell cycle progression
C) Causes no change in the cell cycle progression
D) Initiates apoptosis

Question

Quizplus · Accepted Answer

p16 is a tumor suppressor gene that inhibits the activity of cyclin-dependent kinases (CDKs), which are necessary for cells to progress through the cell cycle. Therefore, the presence of p16 would lead to a decrease in cell cycle progression.

Predict the Effect of P16 on the Cell Cycle of Dividing