If a patient had hemoglobin S and hemoglobin A identified by electrophoresis and a positive hemoglobin solubility test, what is the patient's most likely condition?
A) Hemoglobin C trait
B) Hemoglobin S/D disease
C) Hemoglobin SC disease
D) Sickle cell trait

Question

Quizplus · Accepted Answer

Sickle cell trait is indicated by the presence of both hemoglobin A (normal hemoglobin) and hemoglobin S (sickle cell hemoglobin) in a patient's blood. The positive hemoglobin solubility test further supports the presence of hemoglobin S, which is characteristic of sickle cell conditions, but the presence of significant hemoglobin A suggests the patient does not have sickle cell disease but rather the trait, which is a milder form.

If a Patient Had Hemoglobin S and Hemoglobin a Identified