Erythropoietic porphyrias are associated with:

Question

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Erythropoietic porphyrias are caused by mutations in the enzymes involved in the heme biosynthetic pathway, leading to the accumulation of porphyrin precursors and the development of symptoms such as skin photosensitivity, hemolytic anemia, and splenomegaly. Abnormal iron metabolism (A) may be seen in some types of porphyrias, but it is not specific to erythropoietic porphyrias. Abnormal globin synthesis (C) is not directly related to porphyrias. DMT1 mutations (D) are associated with iron metabolism disorders, but not with porphyrias.

Erythropoietic Porphyrias Are Associated With