Howell-Jolly bodies are red cell inclusions associated with what disease state?
A) Lead poisoning
B) G6PD deficiency
C) Megaloblastic anemia
D) Normal reticulocytes

Question

Quizplus · Accepted Answer

Howell-Jolly bodies are seen in megaloblastic anemia, a condition characterized by impaired DNA synthesis and maturation of red blood cells leading to macrocytic anemia. The presence of Howell-Jolly bodies is indicative of splenic dysfunction, as the spleen normally removes these inclusions from the circulation.

Howell-Jolly Bodies Are Red Cell Inclusions Associated with What Disease