According to research conducted by Japan's Institute of Public Health, patterns of work behavior that include extremely long hours that interfere with normal recovery and rest patterns and high-pressure work without breaks lead to the fatal

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The term "Karoshi syndrome" refers to death from overwork, which is caused by stress and exhaustion from working long hours under high pressure without adequate rest or break time. The other options, such as Angelman syndrome, Hikikomori phenomenon, and Kodokushi phenomenon are not related to the harmful effects of overwork.

According to Research Conducted by Japan's Institute of Public Health