The following are major steps in the process of endochondral ossification: 1. Bone forms at the diaphysis surface.
2) Secondary ossification centers form in the epiphyses.
3) Chondrocytes enlarge and calcify.
4) Osteoclasts create a marrow cavity.
5) Blood vessels invade the inner cartilage and new osteoblasts form spongy bone at a primary ossification center.
The correct order for these events is
A) 3, 1, 5, 4, 2.
B) 1, 3, 5, 4, 2.
C) 1, 5, 3, 4, 2.
D) 2, 3, 1, 5, 4.
E) 3, 1, 4, 5, 2.

Question

Quizplus · Accepted Answer

The correct sequence for endochondral ossification begins with chondrocytes enlarging and calcifying (3), followed by the formation of bone at the diaphysis surface (1). Next, blood vessels invade the inner cartilage, leading to the formation of a primary ossification center where new osteoblasts form spongy bone (5). Osteoclasts then create a marrow cavity (4), and finally, secondary ossification centers form in the epiphyses (2).

The Following Are Major Steps in the Process of Endochondral