Esters are more electrophilic then amides.

Question

Quizplus · Accepted Answer

Esters have a carbonyl group attached to an oxygen atom, which makes them more electrophilic than amides that have a nitrogen atom attached to the carbonyl group. The oxygen atom has a higher electronegativity than nitrogen, and it withdraws electron density from the carbonyl carbon, making it more susceptible to attack by nucleophiles. Therefore, esters are more reactive towards nucleophilic substitution reactions than amides.

Esters Are More Electrophilic Then Amides