E1 reactions are usually less stereoselective than E2 reactions.

Question

Quizplus · Accepted Answer

E1 reactions often lead to a mixture of products due to the formation of a carbocation intermediate, which can lead to different products based on its reorganization or the site of deprotonation. E2 reactions, on the other hand, typically proceed through a concerted mechanism that often leads to more stereoselective outcomes, as the geometry of the transition state can favor the formation of one product over another.

E1 Reactions Are Usually Less Stereoselective Than E2 Reactions