The scissile C-H bond must be antiperiplanar to the leaving group in an E1 reaction.

Question

Quizplus · Accepted Answer

In an E1 reaction, the requirement for the scissile C-H bond to be antiperiplanar to the leaving group applies to E2 reactions, not E1. E1 reactions involve a two-step mechanism where the leaving group departs first, forming a carbocation intermediate, without the necessity for a specific geometric orientation between the C-H bond and the leaving group.

The Scissile C-H Bond Must Be Antiperiplanar to the Leaving