All clotting factors, except for factor VIII and von Willebrand factor, are produced in the:

Question

Quizplus · Accepted Answer

The liver synthesizes and secretes most of the clotting factors, including fibrinogen, prothrombin, factors VII, IX, X, XI, and XIII, as well as protein C and protein S. Factors VIII and von Willebrand factor are produced in endothelial cells and megakaryocytes, respectively, not in the liver. The lymph nodes and spleen are not involved in the production of clotting factors.

All Clotting Factors, Except for Factor VIII and Von Willebrand