Raynaud phenomenon is considered to be one of the first signs of:

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Raynaud phenomenon is a vasospastic disorder of the peripheral blood vessels, and it is considered to be one of the first signs of scleroderma. It is characterized by the narrowing of blood vessels, usually in the fingers and toes, in response to cold temperatures or emotional stress. Melkersson-Rosenthal syndrome is a rare neurological disorder that presents with facial paralysis, swelling of the face and lips, and a fissured tongue. Erythema multiforme is a type of hypersensitivity reaction that presents with skin rash, blisters, and ulcers, usually in response to infections or medications. Crohn's disease is a type of inflammatory bowel disease that affects the gastrointestinal tract, and it presents with symptoms such as abdominal pain, diarrhea, and weight loss.

Raynaud Phenomenon Is Considered to Be One of the First