A major problem in applying the M'Naghten rule to the insanity defense is determining:

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The M'Naghten rule requires that the defendant must have a "disease of the mind" at the time of the crime to be considered insane. However, determining what qualifies as a "disease of the mind" can be a major problem in applying this rule to the insanity defense. There is no clear definition of this term, which can lead to inconsistent and subjective interpretations among different courts and legal experts.

A Major Problem in Applying the M'Naghten Rule to the Insanity