A nurse caring for a client who has been on cyclosporine for six months following a renal allograft reviews the laboratory data and notes that the blood urea nitrogen and serum creatinine have shown a consistent elevation in the last two weeks.The nurse would correctly identify these findings as indicating which problem?

Question

Quizplus · Accepted Answer

Cyclosporine is an immunosuppressant medication used to prevent rejection of transplanted organs. However, it can cause nephrotoxicity, which is evident by increased blood urea nitrogen (BUN) and serum creatinine levels. The consistent elevation in these levels in the last two weeks indicates that the client might be experiencing cyclosporine side effects, specifically nephrotoxicity, which requires further evaluation and management. Metabolic acidosis, metastatic carcinoma, and an anaphylactic reaction do not typically result in elevated BUN and serum creatinine levels.

A Nurse Caring for a Client Who Has Been on Cyclosporine