Aspirin Has Which Adverse Effect on the Gastrointestinal Mucosa

Aspirin has which adverse effect on the gastrointestinal mucosa?

A) Aspirin causes direct cellular injury as it is absorbed across the stomach mucosa.
B) Because all aspirin products have an enteric coating,there is no topical damage to the stomach.
C) After aspirin is systemically absorbed,it inhibits COX-2.
D) Aspirin enhances the effect of prostaglandins' protective function to the GI mucosa.