The Client Tells the Nurse,The Doctor Is Going to Start

The client tells the nurse,The doctor is going to start me on Botox for the muscle spasms in my neck.I've always wanted to try that.It will make me look younger." Which information should the nurse provide to this client regarding onabotulinumtoxinA (Botox) ?
Select all that apply.

A) Once you start on the medication,it may take a week or so before you notice a change in your skin."
B) Be certain you take the medication with a full glass of water because it can be hard on your kidneys."
C) There are many different uses for that drug,depending on how it is administered."
D) You may have to have additional treatments with the medication in a few months."
E) You should be aware that side effects of the medication can occur hours or weeks after your treatment."