A client diagnosed with hypertension is prescribed carvedilol (Coreg)and complains of dizziness and faintness immediately after taking this medication.The nurse knows that this effect is due to the action of which receptors?

Question

Quizplus · Accepted Answer

Carvedilol is a non-selective beta-adrenergic antagonist that also has alpha-adrenergic blocking activity, meaning it blocks the activation of alpha1 and beta1 and beta2 receptors. This blockade of alpha1 receptors can cause vasodilation, leading to a drop in blood pressure and dizziness/faintness. The blockade of beta1 receptors in the heart can also lower heart rate and cardiac output, contributing to hypotension and dizziness. Beta2 receptors are not usually involved in blood pressure regulation and therefore not relevant in this case. Therefore, the main receptors involved in the dizziness and faintness seen with carvedilol use are alpha1 and beta1.

A Client Diagnosed with Hypertension Is Prescribed Carvedilol (Coreg)and Complains