A client is receiving an antiviral drug that is a substrate of the CYP3A4 enzyme system.When a drug that is an inhibitor of the 3A4 system is added to the client's regimen,the nurse should assess the client for which result?

Question

Quizplus · Accepted Answer

When a drug that inhibits the CYP3A4 system is added to the client's regimen, the metabolism of the antiviral drug may be slowed down, resulting in higher levels of the drug in the body. This may increase the risk of toxicity associated with the antiviral drug. Therefore, the nurse must assess the client for any sign of toxicity or adverse reactions. Choices B, C, and D are incorrect because an inhibitor of the CYP3A4 system may not affect the viral-related symptoms, side effects of the antiviral drug or viral load.

A Client Is Receiving an Antiviral Drug That Is a Substrate