Place the following events involved in drug addiction in the correct sequence.
I-The synapse becomes less sensitive,and normal function can only continue in the presence of the drug.
II-CNS responds to increased firing by decreasing the number of drug receptors on the cell membrane.
III-Drug molecule prevents receptor endocytosis and causes overstimulation of the postsynaptic cell.
A)I,II,III
B)III,II,I
C)II,III,I
D)III,I,II

Question

Place the following events involved in drug addiction in the correct sequence.
 I-The synapse becomes less sensitive,and normal function can only continue in the presence of the drug.
II-CNS responds to increased firing by decreasing the number of drug receptors on the cell membrane.
III-Drug molecule prevents receptor endocytosis and causes overstimulation of the postsynaptic cell.
A)I,II,III
B)III,II,I
C)II,III,I
D)III,I,II

Quizplus · Accepted Answer

First, the drug molecule prevents receptor endocytosis and causes overstimulation of the postsynaptic cell (III). As a result of this overstimulation, the CNS responds to increased firing by decreasing the number of drug receptors on the cell membrane (II). Finally, the synapse becomes less sensitive, and normal function can only continue in the presence of the drug (I). Therefore, the correct sequence is III, II, I. Choice B is the only option that has this sequence.

Place the Following Events Involved in Drug Addiction in the Correct