Genetic studies have found that Charcot-Marie-Tooth may be caused by a mutation in the gene Mitofusin-2 (MFN2),which causes mitochondria to form large clumps.In what area of a neuron are these clumps most likely to cause a problem?
A)axon
B)synapse
C)soma
D)dendrite
E)myelin

Question

Quizplus · Accepted Answer

Charcot-Marie-Tooth is a disease that primarily affects the peripheral nerves, particularly those responsible for motor and sensory function in the limbs. The axons of these nerves are responsible for transmitting electrical signals from the neuron's cell body to the muscles and sensory receptors in the limbs. Mutations in MFN2 cause the mitochondria to form large clumps, which can lead to problems with axonal transport and function. Therefore, these clumps are most likely to cause a problem in the axons of the peripheral nerves.

Genetic Studies Have Found That Charcot-Marie-Tooth May Be Caused by a Mutation