Two 6-base sequences are present in bacterial promoters: TATAAT (located 10 nt upstream from the start site)and TTGACA (located 35 nt upstream from the start site).What is the significance of the fact that these two base sequences are different?
A)Binding sites for both the holoenzyme and ATP are provided.
B)Both the location of the start site and the direction of transcription can be established.
C)Binding sites for both the core polymerase and holoenzyme are provided.
D)The transcription bubble can be properly formed.
E)It allows RNA polymerase to distinguish between the template strand and the coding strand of the DNA molecule.

Question

Quizplus · Accepted Answer

The presence of distinct sequences at -10 (TATAAT) and -35 (TTGACA) positions in bacterial promoters allows RNA polymerase to recognize the start site of transcription and the direction in which transcription will proceed, ensuring accurate gene expression.

Two 6-Base Sequences Are Present in Bacterial Promoters: TATAAT (Located