If the effector protein phospholipase C failed to cleave phosphatidylinositol-4,5-bisphosphate (PIP₂),the action of what enzyme would be affected? A)cAMP B)IP₃ C)protein kinase A (PKA) D)protein kinase C (PKC)

Question

Quizplus · Accepted Answer

Phospholipase C cleaves phosphatidylinositol-4,5-bisphosphate (PIP2) to produce inositol-1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), which activate protein kinase C (PKC). Therefore, if PIP2 is not cleaved due to the failure of phospholipase C, the action of PKC would be affected.

If the Effector Protein Phospholipase C Failed to Cleave Phosphatidylinositol-4,5-Bisphosphate