In individuals with normal blood sugar levels,glucose is reabsorbed into the bloodstream in the kidney by members of the GLUT transporter family,which form an aqueous pore across the membrane through which glucose can move passively.As a result,no glucose is excreted in urine.However,in people with untreated diabetes mellitus,blood sugar levels are high and glucose is often present in the urine.What can explain this occurrence?
A)High blood glucose levels reverse the concentration gradient,allowing untransported glucose to be excreted in urine.
B)High blood glucose levels interfere with the coupled transport of water and glucose,allowing untransported glucose to be excreted in urine.
C)The GLUT transporters become saturated,allowing untransported glucose to be excreted in urine.
D)The GLUT transporters cannot hydrolyze ATP quickly enough for ATP to transport the extra glucose,thereby allowing untransported glucose to be excreted in urine.

Question

Quizplus · Accepted Answer

When blood glucose levels are high, the GLUT transporters become saturated with glucose, meaning that there are no more transporters available to transport the excess glucose. As a result, some of the glucose is not reabsorbed and is instead excreted in the urine. This is known as glucosuria.

In Individuals with Normal Blood Sugar Levels,glucose Is Reabsorbed into the Bloodstream