A 50-Year-Old Woman Calls the Clinic Because She Has Noticed

A 50-year-old woman calls the clinic because she has noticed some changes in her body and breasts and wonders if these changes could be attributable to the hormone replacement therapy (HRT) she started 3 months earlier. How should the nurse respond?

A) "HRT is at such a low dose that side effects are very unusual."
B) "HRT has several side effects, including fluid retention, breast tenderness, and vaginal bleeding."
C) "Vaginal bleeding with HRT is very unusual; I suggest you come into the clinic immediately to have this evaluated."
D) "It sounds as if your dose of estrogen is too high; I think you may need to decrease the amount you are taking and then call back in a week."