The drastic phenotypic differences between large dogs, such as bloodhounds, and small dogs, such as Chihuahuas, are a result of

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The phenotypic differences between different breeds of dogs have been selectively bred by humans over thousands of years, resulting in specific traits being emphasized and exaggerated. This process of intentional breeding has resulted in the vast array of dog breeds we see today, with varying sizes, shapes, and temperaments.

The Drastic Phenotypic Differences Between Large Dogs, Such as Bloodhounds