Binding of NAD⁺ to the SIR2 protein causes activation of the histone deacetylase and compaction of the chromatin,silencing of the rDNA locus,reduction of the budding process,and an extended replicative life span for the yeast.

Question

Quizplus · Accepted Answer

Binding of NAD⁺ to SIR2 protein does indeed cause activation of the histone deacetylase and leads to changes such as chromatin compaction, rDNA locus silencing, reduction in budding process, and extended replicative life span in yeast.

Binding of NAD+ to the SIR2 Protein Causes Activation of the Histone

Binding of NAD⁺ to the SIR2 Protein Causes Activation of the Histone