Cloning of the daf-2 gene and identification of the DAF-2 protein as an insulin/IGF-1-like receptor indicate that gene regulation leading to increased life span of the adult worm is under ______ control.

Question

Quizplus · Accepted Answer

The identification of the DAF-2 protein as an insulin/IGF-1-like receptor indicates that the gene regulation leading to increased life span is under neuroendocrine control. Insulin and IGF-1 are both hormones that are involved in metabolic regulation, but they are secreted by neuroendocrine cells in response to various environmental cues. Therefore, while there may be some metabolic and nutritional components to the regulation of this gene, the primary control appears to be neuroendocrine.

Cloning of the Daf-2 Gene and Identification of the DAF-2