George Annas believes that, historically,

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Annas argues that historically, prenatal screening has been used to find conditions that could be used to justify the view that abortion is permissible because the fetus would be better off dead. He cites examples of conditions such as Down syndrome and spina bifida, which have been used in this way. However, he also acknowledges that in recent years, there has been a shift towards using prenatal screening to identify conditions that could be rectified by genetic therapies, such as cystic fibrosis.

George Annas Believes That, Historically