Which principle is most closely associated with the Hippocratic directive to help?

Question

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The principle of beneficence is closely associated with the Hippocratic directive to help. This principle relates to the obligation to act in a way that benefits others and promotes their well-being. Helping others is a fundamental aspect of this principle and is central to the Hippocratic oath. The other principles listed (difference, double effect, and totality) are not directly related to the directive to help.

Which Principle Is Most Closely Associated with the Hippocratic Directive