The nurse caring for a patient with schizophrenia spectrum disorder knows that the risk of disease increases according to which neurochemical explanations? Select all that apply.

Question

Quizplus · Accepted Answer

1. There are a number of neurochemical explanations for schizophrenia spectrum disorder (SSD). The most common is the dopamine hypothesis, which states that the most effective antipsychotic medications may have antagonistic actions on the dopamine type 2 (D2) receptor in the brain. Therefore, drugs that increase (not decrease) dopaminergic activity would produce a condition that resembles psychosis. Another explanation lies with neuropathology, which suggests that SSDs are composed of structural defects in multiple areas with a reduction (not increase) of gray matter in the anterior cingulate, bilateral frontal lobe, hippocampus, and amygdala. A study on brain metabolism dysfunction posits that there is a presence of mitochondrial dysfunction in patients with SSD that results in reduced mitochondrial density and volume, as well as defective mitochondrial energy production.
4. There are a number of neurochemical explanations for schizophrenia spectrum disorder (SSD). The most common is the dopamine hypothesis, which states that the most effective antipsychotic medications may have antagonistic actions on the dopamine type 2 (D2) receptor in the brain. Therefore, drugs that increase (not decrease) dopaminergic activity would produce a condition that resembles psychosis. Another explanation lies with neuropathology, which suggests that SSDs are composed of structural defects in multiple areas with a reduction (not increase) of gray matter in the anterior cingulate, bilateral frontal lobe, hippocampus, and amygdala. A study on brain metabolism dysfunction posits that there is a presence of mitochondrial dysfunction in patients with SSD that results in reduced mitochondrial density and volume, as well as defective mitochondrial energy production.
5. There are a number of neurochemical explanations for schizophrenia spectrum disorder (SSD). The most common is the dopamine hypothesis, which states that the most effective antipsychotic medications may have antagonistic actions on the dopamine type 2 (D2) receptor in the brain. Therefore, drugs that increase (not decrease) dopaminergic activity would produce a condition that resembles psychosis. Another explanation lies with neuropathology, which suggests that SSDs are composed of structural defects in multiple areas with a reduction (not increase) of gray matter in the anterior cingulate, bilateral frontal lobe, hippocampus, and amygdala. A study on brain metabolism dysfunction posits that there is a presence of mitochondrial dysfunction in patients with SSD that results in reduced mitochondrial density and volume, as well as defective mitochondrial energy production.

The Nurse Caring for a Patient with Schizophrenia Spectrum Disorder