Drugs such as the antimalaria drug pyrimethamine inhibit the action of:

Question

Quizplus · Accepted Answer

Pyrimethamine inhibits the action of dihydrofolate reductase, an enzyme required for the synthesis of tetrahydrofolate, the active form of folate. This leads to a depletion of folate, which is essential for DNA synthesis and cell division. Consequently, pyrimethamine is used as an antimalarial drug and in combination with sulfonamides for the treatment of toxoplasmosis and other protozoal infections.

Drugs Such as the Antimalaria Drug Pyrimethamine Inhibit the Action