The chemotherapeutic agent methotrexate has multiple antagonistic effects on:

Name: The chemotherapeutic agent methotrexate has multiple antagonistic effects on:
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Methotrexate is an antagonist of folic acid. It acts by inhibiting the enzyme dihydrofolate reductase, which is responsible for the conversion of dihydrofolic acid to tetrahydrofolic acid, a necessary step in the synthesis of nucleic acid. As a result, the cell cannot synthesis DNA, RNA, and protein, which ultimately leads to cell death.

The Chemotherapeutic Agent Methotrexate Has Multiple Antagonistic Effects On