In alcoholic cirrhosis,hepatocellular damage is caused by:
A) Acetaldehyde accumulation
B) Bile toxicity
C) Acidosis
D) Fatty infiltrations

Question

Quizplus · Accepted Answer

Alcoholic cirrhosis is caused by the toxic effects of alcohol metabolism on the liver.Alcohol is transformed to acetaldehyde,and excessive amounts significantly alter hepatocyte function and activate hepatic stellate cells,a primary cell involved in liver fibrosis.
Bile toxicity does not cause alcoholic cirrhosis.
Acidosis does not cause alcoholic cirrhosis.
Fatty infiltrations do not cause alcoholic cirrhosis.

In Alcoholic Cirrhosis,hepatocellular Damage Is Caused By