Predict the major product of the following reaction.

Question

Quizplus · Accepted Answer

The reaction is a Gabriel synthesis, which involves the addition of an amine to a carbonyl group. The amine used in this reaction is NH2NH2, which is a strong nucleophile. The carbonyl group in this case is the carbonyl group in the acid chloride. The strong nucleophilic attack by NH2NH2 on the acid chloride will lead to the formation of an intermediate, which will then undergo intramolecular cyclization to form the product II.

Predict the Major Product of the Following Reaction