Predict the major product(s)of the following reaction.

Question

Quizplus · Accepted Answer

The reaction will undergo a Friedel-Crafts acylation with acetyl chloride being the acylating agent. This will lead to the substitution of the hydrogen atom in position 2 of the benzene ring. Only II and IV have the correct substitution pattern. Option A is incorrect because only I has a different substitution pattern. Option C is incorrect because III has two acetyl groups attached to the benzene ring and this is unlikely to occur with the steric hindrance in the ortho position. Option D is incorrect because only I has a different substitution pattern.

Predict the Major Product(s)of the Following Reaction