Which of these statements represents long-loop, negative feedback in the CRH-ACTH-cortisol system
A)Cortisol inhibits CRH secretion.
B)CRH inhibits ACTH secretion.
C)ACTH inhibits CRH secretion.
D)ACTH inhibits cortisol secretion.

Question

Quizplus · Accepted Answer

Cortisol inhibits CRH secretion, exemplifying long-loop negative feedback in the hypothalamic-pituitary-adrenal (HPA) axis. This mechanism helps regulate the stress response and maintain homeostasis by reducing the secretion of CRH (Corticotropin-releasing hormone) when cortisol levels are high.

Which of These Statements Represents Long-Loop, Negative Feedback in the CRH-ACTH-Cortisol