Which of these statements is correct concerning an EPP? A)It occurs because of Na⁺ movement inward at the motor end plate region as a result of permeability changes induced by binding of acetylcholine with end-plate receptor sites. B)It is usually smaller in magnitude than an IPSP. C) It is terminated when Ca²⁺ inactivates acetylcholine. D) It is a graded potential similar to IPSP.

Question

Quizplus · Accepted Answer

The EPP (end-plate potential) occurs due to the binding of acetylcholine with end-plate receptor sites, which leads to permeability changes resulting in inward movement of Na+ and K+ ions at the motor end plate region. This makes option A correct. Option B is incorrect as the EPP can be larger in magnitude than an IPSP. Option C is incorrect as the EPP is terminated by the action of acetylcholinesterase, not Ca2+. Option D is incorrect as the EPP is not a graded potential like an IPSP, but rather an all-or-nothing event.

Which of These Statements Is Correct Concerning an EPP