Why can't the large, negatively charged intracellular proteins (A^-) permeate the cell membrane? A)They are greater than 0.8 nm in diameter and are not lipid soluble. B)There are carriers for them. C) No concentration or electrical gradient exists for them. D) There are no positively charged ions to carry them.

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Quizplus · Accepted Answer

Large, negatively charged intracellular proteins such as A^- cannot permeate the cell membrane because they are too big and not lipid soluble. The cell membrane only allows small, lipid-soluble molecules to pass through freely, while larger substances require specialized transport mechanisms. Additionally, due to their negative charge, these proteins would not be able to pass through the hydrophobic portion of the membrane, which is primarily made up of nonpolar fatty acid chains.

Why Can't the Large, Negatively Charged Intracellular Proteins (A-) Permeate

Why Can't the Large, Negatively Charged Intracellular Proteins (A^-) Permeate